Proteoliposomes – ideal model systems for membrane protein analysis

Mar 25, 2022 | Proteins, Proteoliposomes

Proteoliposomes – ideal model systems to study the structure and function of membrane proteins in semi-native environment by cryogenic electron microscopy What are Proteoliposomes ? Proteoliposomes are lipid vesicles containing membrane proteins that can be used as...

The nucleocapsid protein of SARS-CoV-2potential target for a vaccine

Mar 25, 2022 | SARS-CoV-2

What is the N-Protein ?The nucleocapsid protein (N protein) of SARS-CoV-2 is a structural protein synthesized by the virus, which plays a key role in the RNA packaging into the nucleocapsid. Its function is to mediate viral assembly through interaction with the viral...

The S-protein receptor binding domain (RBD) potential uses for SARSCoV immunization and detection

Mar 20, 2022 | Proteins, RBD protein, SARS-CoV-2

The S-protein receptor binding domain (RBD) of SARS-CoV-2 has been the subject of a thorough characterization and its importance in virus infection is well known. The potential uses of RBD of S-protein as a vaccine and as an antigen for the specific and sensitive...

Which extract is best for cell-free protein expression wheat germ or E. coli?

Mar 20, 2022 | Biotech, Cell-Free

Cell-free protein expression offers a rapid, reliable technique for synthesis of proteins. Successfully synthesizing large quantities of high-quality product requires finding the optimal protein expression conditions, such as the type of cellular extract used. Lysate...

Five reasons to label your proteins for NMR studies using cell-free systems

Mar 20, 2022 | Cell-Free, Proteins

Isotope labelling has been used for over 40 years to facilitate the study of protein structure using nuclear magnetic resonance (NMR) spectroscopy. During that time, traditional expression systems such as in vivo protein synthesis were the preferred options for...

Can we use cell-free biotechnology to fight COVID-19?

Mar 20, 2022 | Cell-Free

With the COVID-19 pandemic still spreading across the globe, the fight is on to rapidly develop efficient solutions for diagnosis and treatment. In the past, cell-free protein expression has been used to produce antibodies against other strains of coronavirus. As...