Juil 24, 2023 | Cell-Free, Protéines
Les plaques amyloïdes sont des agrégats de protéines présentant une structure fibrillaire non ramifiée typique, qui sont impliqués dans plusieurs maladiesliées au mauvais repliement des protéines, associées à des maladies neurodégénératives telles que les maladies...
Sep 16, 2022 | Blog, Cell-Free, Protéines
Cell-free protein synthesis (CFPS) technology has experienced an impressive growth in recent years in what concerns applications and the types of molecules that it can advantageously produce. One example is the synthesis of enzymes. Advantages of CFPS for enzyme...
Mar 25, 2022 | Cell-Free, Protéines, Proteoliposomes
Synthelis’ cell-free liposome-based expression system was applied in the development of an OprF vaccine against Pseudomonas aeruginosa. The complete OprF outer membrane protein of P. aeruginosa was used as the immunogen and was expressed in its native form in...
Mar 25, 2022 | Protéines, Proteoliposomes
Proteoliposomes – ideal model systems to study the structure and function of membrane proteins in semi-native environment by cryogenic electron microscopy What are Proteoliposomes ? Proteoliposomes are lipid vesicles containing membrane proteins that can be used as...
Mar 25, 2022 | SARS-CoV-2
What is the N-Protein ?The nucleocapsid protein (N protein) of SARS-CoV-2 is a structural protein synthesized by the virus, which plays a key role in the RNA packaging into the nucleocapsid. Its function is to mediate viral assembly through interaction with the viral...
Mar 20, 2022 | Protéine RBD, Protéines, SARS-CoV-2
The S-protein receptor binding domain (RBD) of SARS-CoV-2 has been the subject of a thorough characterization and its importance in virus infection is well known. The potential uses of RBD of S-protein as a vaccine and as an antigen for the specific and sensitive...
Mar 20, 2022 | Biotech, Cell-Free
Cell-free protein expression offers a rapid, reliable technique for synthesis of proteins. Successfully synthesizing large quantities of high-quality product requires finding the optimal protein expression conditions, such as the type of cellular extract used. Lysate...
Mar 20, 2022 | Cell-Free, Protéines
Isotope labelling has been used for over 40 years to facilitate the study of protein structure using nuclear magnetic resonance (NMR) spectroscopy. During that time, traditional expression systems such as in vivo protein synthesis were the preferred options for...
