Current challenges and perspectives in proteoliposome research

Jun 17, 2024 | Blog, Proteins

Membrane proteins (MPs) are very important in cells as they accomplish a diversity of roles, justifying the increasing interest in their study. However, functional studies of MPs within a native cellular setting are difficult to perform due to the innate complexity of...

iGEM Sponsoring

Apr 15, 2024 | News, Uncategorized

Synthelis est fier d’offrir des opportunités de parrainage à toutes les équipes participant à l’iGEM Grand Jamboree 2024.  Pour améliorer le succès des équipes participantes, nous offrons des kits d’expression de protéines sans cellules Syn-Xpress®,...

Sanofi Idea-Tech Awards

Feb 1, 2024 | News, Uncategorized

Synthelis est très fière d’être l’un des lauréats de l’initiative européenne Sanofi iDEA-TECH Awards dans la catégorie “Processes in Chemistry, Manufacturing, and Control”. Le projet et la technologie acellulaire de Synthelis ont été...

Synthelis devient Synthelis Biotech

Jan 23, 2024 | News, Uncategorized

Nous sommes ravis de vous informer que Vincent Poher, spécialiste du diagnostic in vitro, a récemment acquis Synthelis, ouvrant ainsi la porte à de passionnantes opportunités et innovations. Lisez l’article complet dans Le Dauphiné Libéré pour découvrir les...

Cell-free systems to produce Virus-Like Particles!

Oct 3, 2023 | Blog, Cell-Free

Les particules pseudovirales (VLP) sont des nanostructures constituées de protéines virales assemblées, dépourvues de matériel génétique viral et donc non infectieuses. Leur intérêt réside dans la possibilité de les utiliser pour transporter et délivrer des...

Cell-free synthesis of amyloid fibrils with favorable functional and analytical features

Jul 24, 2023 | Cell-Free, Proteins

Les amyloïdes sont des agrégats de protéines présentant une structure fibrillaire non ramifiée typique, qui sont impliqués dans plusieurs maladies de mauvais repliement des protéines, associées à des maladies neurodégénératives telles que les maladies...

New trends in cell-free Synthetic Biology

May 15, 2023 | Cell-Free

Cell-free Synthetic Biology takes use of biomolecular reactions outside cells to synthesise specific products with applications in medicine, agriculture, environment and industry, particularly in the fields of drug discovery, diagnostics, biomanufacturing and...

Cell-free protein synthesis systems the best chance for your project to succeed!

Mar 25, 2022 | Cell-Free

Do you have a protein you want to express? Are you wondering which technology will provide you with the best results? Have you considered turning to a cell-free system? In comparison to traditional protein expression systems, cell-free protein synthesis can provide a...

Cell-free expressed OprF proteoliposomes as effective vaccine against Pseudomonas aeruginosa?

Mar 25, 2022 | Cell-Free, Proteins, Proteoliposomes

Synthelis’ cell-free liposome-based expression system was applied in the development of an OprF vaccine against Pseudomonas aeruginosa. The complete OprF outer membrane protein of P. aeruginosa was used as the immunogen and was expressed in its native form in...

Proteoliposomes – ideal model systems for membrane protein analysis

Mar 25, 2022 | Proteins, Proteoliposomes

Proteoliposomes – ideal model systems to study the structure and function of membrane proteins in semi-native environment by cryogenic electron microscopy What are Proteoliposomes ? Proteoliposomes are lipid vesicles containing membrane proteins that can be used as...