Oct 3, 2023 | Blog, Cell-Free
Les particules pseudovirales (VLP) sont des nanostructures constituées de protéines virales assemblées, dépourvues de matériel génétique viral et donc non infectieuses. Leur intérêt réside dans la possibilité de les utiliser pour transporter et délivrer des...
Juil 24, 2023 | Cell-Free, Protéines
Les plaques amyloïdes sont des agrégats de protéines présentant une structure fibrillaire non ramifiée typique, qui sont impliqués dans plusieurs maladiesliées au mauvais repliement des protéines, associées à des maladies neurodégénératives telles que les maladies...
Sep 16, 2022 | Blog, Cell-Free, Protéines
Cell-free protein synthesis (CFPS) technology has experienced an impressive growth in recent years in what concerns applications and the types of molecules that it can advantageously produce. One example is the synthesis of enzymes. Advantages of CFPS for enzyme...
Mar 25, 2022 | Cell-Free, Protéines, Proteoliposomes
Synthelis’ cell-free liposome-based expression system was applied in the development of an OprF vaccine against Pseudomonas aeruginosa. The complete OprF outer membrane protein of P. aeruginosa was used as the immunogen and was expressed in its native form in...
Mar 20, 2022 | Biotech, Cell-Free
Cell-free protein expression offers a rapid, reliable technique for synthesis of proteins. Successfully synthesizing large quantities of high-quality product requires finding the optimal protein expression conditions, such as the type of cellular extract used. Lysate...
Mar 20, 2022 | Cell-Free, Protéines
Isotope labelling has been used for over 40 years to facilitate the study of protein structure using nuclear magnetic resonance (NMR) spectroscopy. During that time, traditional expression systems such as in vivo protein synthesis were the preferred options for...