Les protéoliposomes OprF exprimés en système Cell-Free comme vaccin efficace contre Pseudomonas aeruginosa ?

Mar 25, 2022 | Cell-Free, Protéines, Proteoliposomes

Synthelis’ cell-free liposome-based expression system was applied in the development of an OprF vaccine against Pseudomonas aeruginosa. The complete OprF outer membrane protein of P. aeruginosa was used as the immunogen and was expressed in its native form in...

Protéoliposomes – systèmes modèles idéaux pour l’analyse des protéines membranaires

Mar 25, 2022 | Protéines, Proteoliposomes

Proteoliposomes – ideal model systems to study the structure and function of membrane proteins in semi-native environment by cryogenic electron microscopy What are Proteoliposomes ? Proteoliposomes are lipid vesicles containing membrane proteins that can be used as...

Le domaine obligatoire de récepteur de S-protéine (RBD) : utilisations potentielles pour l’immunisation et le dépistage SARS-CoV-2

Mar 20, 2022 | Protéine RBD, Protéines, SARS-CoV-2

The S-protein receptor binding domain (RBD) of SARS-CoV-2 has been the subject of a thorough characterization and its importance in virus infection is well known. The potential uses of RBD of S-protein as a vaccine and as an antigen for the specific and sensitive...

Cinq raisons d’étiqueter vos protéines pour les études NMR utilisant des systèmes Cell-Free

Mar 20, 2022 | Cell-Free, Protéines

Isotope labelling has been used for over 40 years to facilitate the study of protein structure using nuclear magnetic resonance (NMR) spectroscopy. During that time, traditional expression systems such as in vivo protein synthesis were the preferred options for...