{"id":4828,"date":"2025-03-22T13:57:56","date_gmt":"2025-03-22T12:57:56","guid":{"rendered":"https:\/\/synthelis.com\/?page_id=4828"},"modified":"2026-03-16T15:15:16","modified_gmt":"2026-03-16T14:15:16","slug":"publications","status":"publish","type":"page","link":"https:\/\/synthelis.com\/en\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

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Publications<\/h1>\n

[\/et_pb_text][et_pb_divider show_divider=”off” _builder_version=”4.16″ _module_preset=”default” width=”100%” height=”50px” global_colors_info=”{}”][\/et_pb_divider][dnxte_button button_text=”Cell-Free” button_link=”https:\/\/synthelis.com\/?page_id=4725\/#publicationscf” btn_icon=”$||divi||400″ btn_icon_color=”#FFFFFF” btn_icon_placement=”left” dnxt_hover_2d=”dnxt-hover-backward” _builder_version=”4.27.4″ _module_preset=”default” btn_fonts_font=”Rufina||||||||” btn_fonts_text_color=”#D2C6D2″ btn_fonts_font_size=”24px” custom_margin=”0px||0px||true|false” custom_padding=”0px||0px||false|false” border_width_all_btn_border=”0px” border_color_all_btn_border=”RGBA(255,255,255,0)” border_color_top_btn_border=”#D2C6D2″ global_colors_info=”{}”][\/dnxte_button][dnxte_button button_text=”Bioluminescence” button_link=”https:\/\/synthelis.com\/?page_id=4725\/#publicationsbio” btn_icon=”$||divi||400″ btn_icon_color=”#FFFFFF” btn_icon_placement=”left” dnxt_hover_2d=”dnxt-hover-backward” _builder_version=”4.27.4″ _module_preset=”default” btn_fonts_font=”Rufina||||||||” btn_fonts_text_color=”#D2C6D2″ btn_fonts_font_size=”24px” custom_margin=”0px||0px||true|false” custom_padding=”0px||0px||false|false” border_width_all_btn_border=”0px” border_color_all_btn_border=”RGBA(255,255,255,0)” border_color_top_btn_border=”#D2C6D2″ global_colors_info=”{}”][\/dnxte_button][et_pb_divider show_divider=”off” _builder_version=”4.16″ _module_preset=”default” width=”100%” height=”50px” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ module_id=”publicationscf” _builder_version=”4.27.4″ _module_preset=”default” background_color=”#FFFFFF” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_font=”PT Serif|700|||||||” header_text_color=”#4D1749″ header_3_font=”PT Serif|700|||||||” header_3_font_size=”30px” header_4_font=”PT Serif|700|||||||” header_4_font_size=”30px” border_color_bottom=”#EEEFF3″ global_colors_info=”{}”]<\/p>\n

Cell-Free Publications<\/h4>\n

[\/et_pb_text][et_pb_divider color=”#D2C6D2″ divider_position=”center” _builder_version=”4.16″ _module_preset=”default” custom_margin=”0px||0px||true|false” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”17px” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” global_colors_info=”{}”]<\/p>\n

Cell-Free Publications Synthelis Biotech<\/strong><\/span><\/p>\n

[\/et_pb_text][et_pb_divider color=”#D2C6D2″ divider_style=”dashed” divider_position=”center” _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”0px||0px||true|false” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.18.0″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

A New in Silico Antibody Similarity Measure Both Identifies Large Sets of Epitope Binders with Distinct CDRs and Accurately Predicts Off-Target Reactivity\u00a0<\/a><\/strong>Musnier, A.; Bourquard, T.; Vallet, A.; Mathias, L.; Bruneau, G.; Ayoub, M.A.; Travert, O.; Corde, Y.; Gallay, N.; Boulo, T.; et al. . <\/a>Int. J. Mol. Sci. <\/span>2022<\/span>, 23<\/span>, 9765. <\/a>https:\/\/doi.org\/10.3390\/<\/span><\/a> ijms23179765<\/a><\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

OprF proteoliposome: a vaccine candidate.<\/strong><\/a> G\u00e9raldine Mayeux, Landry Gayet, Lavinia Liguori, Marine Odier, Donald K Martin, Sandra Cort\u00e8s, B\u00e9atrice Schaack, Jean-Luc Lenormand Life Science Alliance mai 2021, 4 (6) e202000958; DOI: 10.26508\/lsa.202000958<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Cholesterol impacts chemokine CCR5 receptor ligand-binding activity.<\/strong><\/a> Pierre Calmet, Christophe Cullin, Sandra Cort\u00e8s, Maylou Vang, Nada Caudy, Rim Baccouch, Jean Dessolin, Nada Taib Maamar, Sophie Lecomte, Bruno Tillier, Isabel D Alves in FEBS J. 2020<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

High throughput cell-free expression: From PCR product design to functionality validation.<\/strong><\/a> Sandra Cort\u00e8s, Fatima-Ezzahra Hibti, Frydman Chiraz, Safia Ezzine in Methods and Protocols. 2019<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Functional characterization of cell-free expressed Kv1.3 channel using a voltage-sensitive fluorescent dye.<\/strong><\/a> Sandra Cort\u00e8s, Caroline Barette, R\u00e9my B\u00e9roud, Michel De Waard, B\u00e9atrice Schaack in Elsevier. 2018<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

A new functional membrane protein microarray based on tethered phospholipid bilayers.<\/strong><\/a> Meriem Chadli, Ofelia Maniti, Christophe Marquette, Bruno Tillier, Sandra Cort\u00e8s and Agn\u00e8s Girard-Egrot in the Analyst. 2018<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

New Tethered Phospholipid Bilayers Integrating Functional G-Protein-Coupled Receptor Membrane Proteins.<\/strong><\/a> Meriem Chadli, Samuel Rebaud, Ofelia Maniti, Bruno Tillier, Sandra Cort\u00e8s, and Agnes Girard-Egrot in Langmuir. 2017<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Coupling neutron reflectivity with cell-free protein synthesis to probe membrane protein structure in supported bilayers.<\/strong><\/a> Thomas Soranzo, Donald K. Martin, Jean-Luc Lenormand, and Erik B. Watkins in Scientific Reports. 2017<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Functional reconstitution of cell-free synthesized purified Kv channels.<\/strong><\/a> St\u00e9phane Renauld , Sandra Cort\u00e8s , Beate Bersch, Xavier Henry, Michel De Waard , B\u00e9atrice Schaack in Biochim Biophys Acta. 2017<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Therapeutic effects of proteoliposomes on X-linked chronic granulomatous disease: proof of concept using macrophages differentiated from patient-specific induced pluripotent stem cells<\/strong><\/a> Julie Brault, Guillaume Vaganay, Aline Le Roy, Jean-Luc Lenormand, Sandra Cort\u00e8s, Marie Jos\u00e9 Stasia in International Journal of Nanomedicine. 2017<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Anti-Tumor Effects of Bak-Proteoliposomes against Glioblastoma<\/strong><\/a> Lavinia, Liguori, Fabio Pastorino , Xavier Rousset, Silvia Alfano, Sandra Cort\u00e8s, Laura Emionite, Antonio Daga, Mirco Ponzoni and Jean-Luc Lenormand in Molecules. 2015<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Functional characterization of p7 viroporin from hepatitis C virus produced in a cell-free expression system.<\/strong><\/a> Soranzo T, Cort\u00e8s S, Gilde F, Kreir M, Picart C, Lenormand JL in Protein Expr Purif. 2015 <\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Recombinant Nox4 cytosolic domain produced by a cell or cell-free base systems exhibits constitutive diaphorase activity.<\/strong><\/a> Nguyen MV, Zhang L, Lhomme S, Mouz N, Lenormand JL, Lardy B, Morel F in Biochem Biophys Res Commun. 2012 16;419(3):453-8.<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Crystallization of the membrane protein hVDAC1 produced in cell-free system.<\/strong><\/a> Deniaud A, Liguori L, Blesneac I, Lenormand JL, Pebay-Peyroula E in Biochim Biophys Acta. 2010 -1798(8):1540-6. <\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Single-step production of functional OEP24 proteoliposomes.<\/strong><\/a> Liguori L, Blesneac I, Madern D, Vivaudou M, Lenormand JL in Protein Expr Purif. 2010 \u2013 69,1 (106-111). <\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Production of recombinant proteoliposomes for therapeutic uses.<\/strong><\/a> Liguori L. and Lenormand JL in Methods in Enzymology, 2009 \u2013 465 (209-223).<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

A bacterial cell-free expression system to produce membrane proteins and proteoliposomes: from cDNA to functional assay.<\/strong><\/a> Liguori L, Marques B, Lenormand JL in Curr Protoc Protein Sci. 2008. Nov;Chapter 5:Unit 5.22.<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Liposomes-mediated delivery of pro-apoptotic therapeutic membrane proteins.<\/strong><\/a> Liguori L, Marques B, Villegas-Mendez A, Rothe R, Lenormand JL in J Control Release. 2008. 20;126(3):217-27.<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Liposome-mediated cellular delivery of active gp91(phox).<\/strong><\/a> Marques B, Liguori L, Paclet MH, Villegas-Mend\u00e9z A, Rothe R, Morel F, Lenormand JL in PLoS One. 2007. 12;2(9):e856. PDF here.<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Production of membrane proteins using cell-free expression systems.<\/strong><\/a> Liguori L, Marques B, Villegas-M\u00e9ndez A, Rothe R, Lenormand JL in Expert Rev Proteomics. 2007. 4(1):79-90. Review.<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.5″ _module_preset=”default” text_font_size=”17px” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n

Cell-Free Publications of interest<\/strong><\/span><\/p>\n

[\/et_pb_text][et_pb_divider color=”#D2C6D2″ divider_style=”dashed” divider_position=”center” _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”0px||0px||true|false” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Liposome chaperon in cell-free membrane protein synthesis: one-step preparation of KcsA-integrated liposomes and electrophysiological analysis by the planar bilayer method.<\/strong><\/a> Ando M, Akiyama M, Okuno D, Hirano M, Ide T, Sawada S, Sasaki T, Akiyoshi K in Biomater Sci 2015<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ module_id=”publicationsbio” _builder_version=”4.27.4″ _module_preset=”default” background_color=”#EEEFF3″ global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_font=”PT Serif|700|||||||” header_text_color=”#4D1749″ header_3_font=”PT Serif|700|||||||” header_3_font_size=”30px” header_4_font=”PT Serif|700|||||||” header_4_font_size=”30px” border_color_bottom=”#EEEFF3″ global_colors_info=”{}”]<\/p>\n

Bioluminescence Publications<\/h4>\n

[\/et_pb_text][et_pb_divider color=”#D2C6D2″ divider_position=”center” _builder_version=”4.16″ _module_preset=”default” custom_margin=”0px||0px||true|false” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”17px” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” global_colors_info=”{}”]<\/p>\n

Substrate chemistry<\/strong><\/span><\/p>\n

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A Gram-scale synthesis of luciferins derived from coelenterazine and original insights into their bioluminescence properties <\/a><\/strong>Coutant et al., Org. Biomol. Chem., 17, 3709 (2019)<\/a><\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Bioluminescence Profiling of NanoKAZ\/NanoLuc Luciferase Using a Chemical Library of Coelenterazine Analogues.<\/strong> Coutant et al., Chem. Eur. J., 26, 948-958 (2020)<\/span><\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.5″ _module_preset=”default” text_font_size=”17px” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n

Neuronal activity<\/strong><\/span><\/p>\n

[\/et_pb_text][et_pb_divider color=”#D2C6D2″ divider_style=”dashed” divider_position=”center” _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”0px||0px||true|false” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Neural engineering with photons as synaptic transmitters.<\/strong> Porta-de-la-Riva et al., Nature Methods (2023)<\/span><\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Bioluminescence as a functional tool for visualizing and controlling neuronal activity in vivo.<\/strong> Porta-de-la-Riva et al., Neurophotonics (2024)<\/span><\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.5″ _module_preset=”default” text_font_size=”17px” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n

Cellular analysis<\/strong><\/span><\/p>\n

[\/et_pb_text][et_pb_divider color=”#D2C6D2″ divider_style=”dashed” divider_position=”center” _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”0px||0px||true|false” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Numb-associated kinases are required for SARS-CoV-2 infection and are cellular targets for antiviral strategies.<\/strong> Karim et al., Antiviral Research 204,105367 (2022)<\/span><\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Full eradication of pre\u2010clinical human papilloma virus\u2010induced tumors by a lentiviral vaccine<\/strong>. Douguet et al., EMBO Molecular Medicine (2023)<\/span><\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.5″ _module_preset=”default” text_font_size=”17px” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n

Fundamental Biology<\/strong><\/span><\/p>\n

[\/et_pb_text][et_pb_divider color=”#D2C6D2″ divider_style=”dashed” divider_position=”center” _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”0px||0px||true|false” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

KCTD5 Forms Hetero-Oligomeric Complexes with Various Members of the KCTD Protein Family<\/strong> Liao et al. International journal of molecular sciences (2023)<\/span><\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Correction: Sarry et al. Host-Specific Interplay between Foot-and-Mouth Disease Virus 3D Polymerase and the Type-I Interferon Pathway. Viruses 2023, 15, 666<\/strong>. Sarry et al., Viruses (2023)<\/span><\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Pivotal role of exogenous pyruvate in human natural killer cell metabolism.<\/strong> Kern et al., Nature Metabolism (2025)<\/span><\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”17px” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” global_colors_info=”{}”]<\/p>\n

Bioluminescence microscopy<\/strong><\/span><\/p>\n

[\/et_pb_text][et_pb_divider color=”#D2C6D2″ divider_style=”dashed” divider_position=”center” _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”0px||0px||true|false” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Volumetric imaging of fast cellular dynamics with deep learning enhanced bioluminescence microscopy<\/strong> Morales-Curiel et al., Communications biology (2022)<\/span><\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”17px” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” global_colors_info=”{}”]<\/p>\n

Immunoassays<\/strong><\/span><\/p>\n

[\/et_pb_text][et_pb_divider color=”#D2C6D2″ divider_style=”dashed” divider_position=”center” _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”0px||0px||true|false” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

A highly sensitive bioluminescent method for measuring allergen-specific IgE in microliter samples<\/strong> Goyard et al., Allergy (2020)<\/span><\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

Prevalence of SARS-CoV-2 antibodies in France: results from nationwide serological surveillance<\/strong> Le Vu et al. Nature Communications (2021)<\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

LuLIPLEX: A Fast, Highly Sensitive, and Multiplexed Method for the Detection of IgE Against Major Allergens<\/strong> Leveque et a., Allergy (2024)<\/span><\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.16″ _module_preset=”default” background_color=”#D2C6D2″ background_enable_image=”off” background_size=”initial” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”1_2″ module_class=”centrer-verticalement” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font=”Rufina||||||||” text_text_color=”#4D1749″ text_font_size=”46px” text_line_height=”40px” custom_margin=”||0px||false|false” text_font_size_tablet=”37px” text_font_size_phone=”35px” text_font_size_last_edited=”on|phone” global_colors_info=”{}”]<\/p>\n

We look
forward to
your questions<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ module_class=”centrer-verticalement” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][dnxte_button button_text=”Contact us” button_link=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI2NCJ9fQ==@” btn_show_hide=”off” dnxt_hover_2d=”dnxt-hover-float” dnxt_hover_bg_color=”#4D1749″ _builder_version=”4.27.4″ _dynamic_attributes=”button_link” _module_preset=”default” btn_fonts_font=”PT Serif||||||||” btn_fonts_text_color=”#FFFFFF” background_color=”#29102E” use_background_color_gradient=”on” background_color_gradient_type=”linear” background_color_gradient_direction=”-90deg” background_color_gradient_stops=”#29102e 0%|#4d1749 100%” background_color_gradient_start=”#29102e” background_color_gradient_end=”#4d1749″ custom_margin=”||||false|false” custom_padding=”20px|60px|20px|60px|true|true” border_width_all_btn_border=”0px” border_color_all_btn_border=”RGBA(255,255,255,0)” box_shadow_style=”preset3″ global_colors_info=”{}”][\/dnxte_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.16″ _module_preset=”default” custom_padding=”0px||0px||true|false” global_colors_info=”{}”][et_pb_row column_structure=”1_3,1_3,1_3″ use_custom_gutter=”on” gutter_width=”1″ make_equal=”on” _builder_version=”4.16″ _module_preset=”default” width=”100%” max_width=”100%” min_height=”70vh” custom_padding=”0px||0px||false|false” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”4.16″ _module_preset=”default” background_image=”http:\/\/synthelis.com\/wp-content\/uploads\/2022\/01\/Synthelis-MemeUneProteineABesoindExprimerSonPotentiel-Part1.jpg” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font=”PT Serif||||||||” text_text_color=”#FFFFFF” text_font_size=”16px” background_layout=”dark” min_height=”50vh” min_height_tablet=”50vh” min_height_phone=”50vh” min_height_last_edited=”on|phone” custom_margin=”0px||||false|false” global_colors_info=”{}”][\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.16″ _module_preset=”default” use_background_color_gradient=”on” background_color_gradient_direction=”45deg” background_color_gradient_stops=”#29102e 6%|#4d1749 65%” background_color_gradient_start=”#29102e” background_color_gradient_start_position=”6%” background_color_gradient_end=”#4d1749″ background_color_gradient_end_position=”65%” custom_padding=”78px|65px|78px|65px|true|true” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font=”Rufina||||||||” text_text_color=”#FFFFFF” text_font_size=”55px” text_line_height=”1em” text_font_size_tablet=”55px” text_font_size_phone=”40px” text_font_size_last_edited=”on|phone” global_colors_info=”{}”]<\/p>\n

Even
a protein
needs
to express
its potential.<\/p>\n

[\/et_pb_text][et_pb_divider show_divider=”off” _builder_version=”4.16″ _module_preset=”default” width=”100%” height=”50px” global_colors_info=”{}”][\/et_pb_divider][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font=”PT Serif||||||||” text_text_color=”#FFFFFF” text_font_size=”16px” background_layout=”dark” custom_margin=”0px||||false|false” global_colors_info=”{}”]<\/p>\n

Cell-Free Systems Applications<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.16″ _module_preset=”default” background_image=”http:\/\/synthelis.com\/wp-content\/uploads\/2022\/01\/Synthelis-MemeUneProteineABesoindExprimerSonPotentiel-Part2.jpg” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font=”PT Serif||||||||” text_text_color=”#FFFFFF” text_font_size=”16px” background_layout=”dark” min_height=”50vh” min_height_tablet=”50vh” min_height_phone=”50vh” min_height_last_edited=”on|phone” custom_margin=”0px||||false|false” global_colors_info=”{}”][\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

Publications

\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t\t$<\/i>Cell-Free<\/a>\n\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>
\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t\t$<\/i>Bioluminescence<\/a>\n\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>Cell-Free PublicationsCell-Free Publications Synthelis BiotechA New in Silico Antibody Similarity Measure Both Identifies Large Sets of Epitope Binders with Distinct CDRs […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_surecart_dashboard_logo_width":"180px","_surecart_dashboard_show_logo":true,"_surecart_dashboard_navigation_orders":true,"_surecart_dashboard_navigation_invoices":true,"_surecart_dashboard_navigation_subscriptions":true,"_surecart_dashboard_navigation_downloads":true,"_surecart_dashboard_navigation_billing":true,"_surecart_dashboard_navigation_account":true,"footnotes":""},"folder":[53],"class_list":["post-4828","page","type-page","status-publish","hentry"],"yoast_head":"\nPublications - Synthelis<\/title>\n<meta name=\"description\" content=\"Explore Synthelis\u2019 scientific publications on cell-free protein expression and bioluminescence technologies\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/synthelis.com\/en\/publications\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publications - 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